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KMID : 0359919950140030410
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Korean Journal of Nephrology
1995 Volume.14 No. 3 p.410 ~ p.416
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A Case of Rhabdomyolysis with Acute Renal Failure Due to Bezafibrate
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Abstract
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Bezafibrate is a lipid-lowering agent which belongs to the fibric acid derivatives. Bezafibrate is chemically similar to clofibrate, the latter is known to induce occainally acute muscular syndrome with or without renal failure. We report a
patient
with
diabetic nephropathy who had massive rhabdomyolysis with acute renal failure due to bezafibrate. A 47-year-old woman was admitted with complaints of general weakness and red urine. She has had rheumatoid arthritis and diabetes mellitus 5 years
ago,
and
mild were noticed since last yea. She was given bezafibrate for the control of hypercholesterolemia for 1 week. Sudden general myalgia. Anorexia, and red urine developed before admissing. Rapid increase in BUN. serum creatinine and muscle enzymes
were
noted. Increased muscle uptake of technetium-99m Mdp were noticed on bone scan These findings suggest that bezafibrate had provoked rhabdomyolysis with acute renal failure.
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KEYWORD
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